EDINSON CAVANI could be handed his first Manchester United start when the club face Istanbul Basaksehir on Wednesday.
Ole Gunnar Solskjaer is set to make a number of changes from the side that lost 1-0 to Arsenal at Old Trafford on Sunday.
Though the Norwegian could persist with his narrow diamond formation he used against the Gunners and RB Leipzig in last week's 5-0 win.
Having won their opening two Group H Champions League matches, Solskjaer could opt to rest a number of key players ahead of Saturday's trip to Everton.
With that in mind, David De Gea could be replaced between the sticks by Dean Henderson – who is yet to feature in Europe this season.
Aaron Wan-Bisska will likely retain his place at right-back, with Luke Shaw to start at left-back as Alex Telles continues to recover from COVID-19.
Solskjaer is likely to reshuffle his defence, with club captain Harry Maguire to potentially keep his place in the line-up.
And he could partner Axel Tuanzebe, with the defender yet to start since his emphatic performance away at Paris Saint-Germain.
Nemanja Matic could be recalled to the starting XI as United's defensive midfielder.
Fred and Paul Pogba could then play together in the middle of the pitch, with Scott McTominay dropped to the bench.
Dutch international Donny van de Beek could replace Bruno Fernandes as the No10, with Jesse Lingard unavailable.
Cavani could then partner Anthony Martial up top, with Rashford and Greenwood rested for the clash at Goodison Park.
Daniel James and Juan Mata are two other options for Solskjaer, though it is unlikely the duo will start.
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